Lyophilized vial
GLP1-SG
Long-acting GLP-1 receptor agonist analogue for metabolic pathway studies.
$160.00
GLP Research · Metabolic
GLP2-TZ
99.84% purity · Lot 00VCS9 · tested May 12, 2026Dual GIP / GLP-1 receptor agonist for incretin-signalling research.
- Independently tested
- Lot-matched COA
- Lyophilized for stability
- Ships from the USA
Research use only. Not for human or veterinary use. Sold to qualified researchers aged 21+.
SizePO-GLP2TZ-10
$100.00
1
Lot-matched documentation. Every order ships with the certificate for its lot. If a vial arrives damaged or doesn't match its paperwork, tell us within 72 hours and we'll replace it.
Latest lab results
Third-party testedGLP2-TZ 10 mg
- Purity (HPLC-UV)
- 99.84%
- Identity (LC-MS)
- Confirmed — GLP-2
- Net content
- 11.09 mg (label 10 mg)
- Lot
- 00VCS9
- Tested
- May 12, 2026
- Lab
- Freedom Diagnostics Testing
Your order ships with the certificate for its own lot. 1 earlier certificate for this size in the COA library.
About GLP2-TZ
Dual GIP / GLP-1 receptor agonist for incretin-signalling research.
Supplied as
10 mg per vial, as a lyophilized powder in a sealed glass vial with a crimped cap. The lot number on the label matches the certificate of analysis in the COA library.
Storage and handling
Store lyophilized powder frozen (−20 °C) or refrigerated, sealed and away from light. Once reconstituted, keep refrigerated (2–8 °C).
Handle in a laboratory setting using appropriate protective equipment. Consult the certificate of analysis and safety data for lot-specific information.
Important research notice. This product is intended solely for in-vitro and laboratory research. It is not a drug, food, supplement or cosmetic, has not been evaluated by the FDA, and must not be used in humans or animals. Peptides Only does not provide usage or dosing information.
Research summary
GLP2-TZ is a 39-residue lipidated peptide that activates two incretin receptors — the glucose-dependent insulinotropic polypeptide (GIP) receptor and the GLP-1 receptor. It is supplied for laboratory research into dual incretin agonism and how the two pathways interact in metabolic regulation.
What is a dual GIP / GLP-1 receptor agonist?
GIP and GLP-1 are the two incretin hormones: gut peptides released after a meal that amplify glucose-dependent insulin secretion1. GIP is secreted by K-cells of the upper small intestine and GLP-1 by L-cells further down; each acts through its own G protein-coupled receptor1,2.
A dual agonist is a single peptide engineered to activate both receptors. Compounds in this class are typically built on a GIP-like sequence with substitutions that confer GLP-1 receptor activity, plus a fatty-acid side chain for albumin binding and a long half-life2,3.
Why researchers study both incretin receptors
GIP was long thought to add little on its own, because its insulin-releasing effect is blunted in some metabolic disease models. Combining GIP receptor and GLP-1 receptor activity in one molecule produced effects in research models that were larger than GLP-1 receptor agonism alone, which made dual agonism a major line of metabolic research2,3.
Limitations of the evidence
How the GIP receptor contributes is still debated: both agonism and antagonism of that receptor have been reported to affect body weight in different models. Results depend on the exact compound and model. This research compound is not a medicine, has not been evaluated by the FDA, and is sold for laboratory research only.
GLP2-TZ FAQ
What does GLP2-TZ act on?
Two receptors: the GIP receptor and the GLP-1 receptor, both class B G protein-coupled receptors of the incretin system1,2.
How is a dual agonist different from a GLP-1 receptor agonist?
A GLP-1 receptor agonist such as GLP1-SG activates one incretin receptor; a dual agonist activates both the GIP and GLP-1 receptors with one molecule2.
Which sizes are available?
10 mg, 30 mg, 60 mg and 100 mg vials of lyophilized peptide, each lot with its own certificate.
How should a lyophilized GLP research peptide be stored?
Sealed vials of lyophilized peptide are kept frozen (−20 °C) or refrigerated, dry and away from light. Peptide storage and stability explains why.
How is each lot verified?
Every lot is tested by an independent laboratory for identity (mass spectrometry) and purity (HPLC). The certificate for the lot on your vial is published in the COA library and linked from this page.
References
- Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology. 2007;132(6):2131-57. PubMed 17498508
- Campbell JE, Drucker DJ. Pharmacology, physiology, and mechanisms of incretin hormone action. Cell Metab. 2013;17(6):819-37. PubMed 23684623
- Finan B, Ma T, Ottaway N, et al. Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans. Sci Transl Med. 2013;5(209):209ra151. PubMed 24174327
Research summary reviewed 2026-10-26 against the cited literature.
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